Washington, D.C. 20549
Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): April 10, 2021
(Exact name of registrant as specified in its charter)
(State or other jurisdiction of
File Number)
(IRS Employer
Identification No.)
225 State Street, 9th Floor
(Address of principal executive offices)(Zip Code)
Registrant’s telephone number, including area code: 857-246-8998
(Former name or former address, if changed since last report.)
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions: 
Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading Symbol(s)Name of each exchange on which registered
Common Stock, $0.001 par value per sharePIRSThe Nasdaq Capital Market
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).
Emerging Growth Company 
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act.  

Item 7.01: Regulation FD Disclosure.
Attached hereto as and incorporated by reference herein are: The Cinrebafusp Alfa American Association for Cancer Research (AACR) Presentation, Dated April 2021 (Exhibit 99.1), the PRS-344 AACR Presentation, Dated April 2021 (Exhibit 99.2), a Press Release of Pieris Pharmaceuticals, Inc., Dated April 10, 2021 (Exhibit 99.3), and the April 2021 Investor Presentation of Pieris Pharmaceuticals, Inc. (Exhibit 99.4).

The information set forth under this “Item 7.01. Regulation FD Disclosure,” including Exhibits 99.1, 99.2, 99.3, and 99.4 attached hereto, shall not be deemed “filed” for any purpose, and shall not be deemed incorporated by reference into any filing under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended, regardless of any general incorporation language in any such filing. except as shall be expressly set forth by specific reference in such filing.

Item 9.01 Financial Statements and Exhibits
(d) Exhibits.

99.1 Cinrebafusp Alfa AACR Presentation, Dated April 2021.

99.2 PRS-344 AACR Poster, Dated April 2021.

99.3 Press Release, Dated April 10, 2021.

99.4 Investor Presentation, Dated April 2021.

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
Dated: April 12, 2021  /s/ Tom Bures
  Tom Bures
  Vice President, Finance